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Common Side Effects Common side effects include: Nausea Diarrhea Vomiting Constipation Stomach pain Decreased appetite Headache Serious Side Effects (Less Common) While serious side effects are rare, they may include: Pancreatitis (inflammation of the pancreas) Gallbladder problems Kidney injury due to dehydration from nausea or vomiting Serious allergic reactions Vision changes in type 2 diabetes patients Increased heart rate Oral semaglutide has a boxed warning for potential thyroid C-cell tumors, as observed in animal studies, and is not recommended for those with a history of medullary thyroid carcinoma
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